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1

Three-Component Coupling of Aldehydes, Aminopyrazoles, and Sulfoxonium Ylides via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrazolo[1,5- a ]pyrimidines

Hoang, Gia L., Streit, Andrew D., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

2

Total Synthesis of (+)-Lithospermic Acid by Asymmetric Intramolecular Alkylation via Catalytic C−H Bond Activation

O'Malley, Steven J., Tan, Kian L., Watzke, Anja, Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

3

Synthesis and Applications of tert-Butanesulfinamide

Robak, MaryAnn T., Herbage, Melissa A., Ellman, Jonathan A.

Journal:

Chemical Reviews

Year:

2010

Language:

english

File:

PDF, 5.48 MB

english, 2010

4

An Alkanesulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis

Backes, Bradley J., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

5

Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation

Ahrendt, Kateri A., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

6

Rhodium(III)-Catalyzed Indazole Synthesis by C–H Bond Functionalization and Cyclative Capture

Lian, Yajing, Bergman, Robert G., Lavis, Luke D., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 760 KB

english, 2013

7

Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C–H Bond Functionalization

Wangweerawong, Apiwat, Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 478 KB

english, 2014

8

Highly Stereoselective Cobalt(III)-Catalyzed Three-Component C−H Bond Addition Cascade

Boerth, Jeffrey A., Hummel, Joshua R., Ellman, Jonathan A.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 998 KB

english, 2016

9

Synthesis and Applications of Small Molecule Libraries

Thompson, Lorin A., Ellman, Jonathan A.

Journal:

Chemical Reviews

Year:

1996

Language:

english

File:

PDF, 1.88 MB

english, 1996

10

N-tert -Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines

Ellman, Jonathan A., Owens, Timothy D., Tang, Tony P.

Journal:

Accounts of Chemical Research

Year:

2002

Language:

english

File:

PDF, 329 KB

english, 2002

11

Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation

Shin, Youngsook, Winans, Katharine A., Backes, Bradley J., Kent, Stephen B. H., Ellman, Jonathan A., Bertozzi, Carolyn R.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 204 KB

english, 1999

12

Catalytic C−O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers

Nichols, Jason M., Bishop, Lee M., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

13

Combinatorial Thinking in Chemistry and Biology

Jonathan Ellman, Barry Stoddard and Jim Wells

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 692 KB

english, 1997

14

Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II

Haque, Tasir S., Skillman, A. Geoffrey, Lee, Christina E., Habashita, Hiromu, Gluzman, Ilya Y., Ewing, Todd J. A., Goldberg, Daniel E., Kuntz, Irwin D., Ellman, Jonathan A.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 218 KB

english, 1999

15

A novel topical minocycline foam for the treatment of moderate-to-severe acne vulgaris: Results of 2 randomized, double-blind, phase 3 studies

Gold, Linda Stein, Dhawan, Sunil, Weiss, Jonathan, Draelos, Zoe Diana, Ellman, Herman, Stuart, Iain A.

Journal:

Journal of the American Academy of Dermatology

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

16

Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades

Hummel, Joshua R., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 359 KB

english, 2015

17

Rhodium Catalyzed Chelation-Assisted C–H Bond Functionalization Reactions

Colby, Denise A., Tsai, Andy S., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Accounts of Chemical Research

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

18

An efficient didehydroxylation method for the biomass-derived polyols glycerol and erythritol. Mechanistic studies of a formic acid-mediated deoxygenation

Arceo, Elena, Marsden, Peter, Bergman, Robert G., Ellman, Jonathan A.

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 576 KB

english, 2009

19

Cobalt(III)-Catalyzed C–H Bond Amidation with Isocyanates

Hummel, Joshua R., Ellman, Jonathan A.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 639 KB

english, 2015

20

Attenuation of autoimmune disease in fas-deficient mice by treatment with a cytotoxic benzodiazepine

Jeffrey J. Bednarski, Roscoe E. Warner, Tharaknath Rao, Francesco Leonetti, Raymond Yung, Bruce C. Richardson, Kent J. Johnson, Jonathan A. Ellman, Anthony W. Opipari Jr., Gary D. Glick

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

21

Mechanism of the Rhodium(III)-Catalyzed Arylation of Imines via C–H Bond Functionalization: Inhibition by Substrate

Tauchert, Michael E., Incarvito, Christopher D., Rheingold, Arnold L., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 667 KB

english, 2012

22

Mechanistic Study of the Oxidative Coupling of Styrene with 2-Phenylpyridine Derivatives Catalyzed by Cationic Rhodium(III) via C–H Activation

Brasse, Mikaël, Cámpora, Juan, Ellman, Jonathan A., Bergman, Robert G.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 322 KB

english, 2013

23

Facile Rh(III)-Catalyzed Synthesis of Fluorinated Pyridines

Chen, Shuming, Bergman, Robert G., Ellman, Jonathan A.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 544 KB

english, 2015

24

Asymmetric Synthesis of (−)-Incarvillateine Employing an Intramolecular Alkylation via Rh-Catalyzed Olefinic C−H Bond Activation

Tsai, Andy S., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

25

Rhodium(III)-Catalyzed Alkenyl CH Bond Functionalization: Convergent Synthesis of Furans and Pyrroles

Lian, Yajing, Huber, Tatjana, Hesp, Kevin D., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 456 KB

english, 2013

26

Facile Synthesis of Unsymmetrical Acridines and Phenazines by a Rh(III)-Catalyzed Amination/Cyclization/Aromatization Cascade

Lian, Yajing, Hummel, Joshua R., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 824 KB

english, 2013

27

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

Backes, Bradley J., Harris, Jennifer L., Leonetti, Francesco, Craik, Charles S., Ellman, Jonathan A.

Journal:

Nature Biotechnology

Year:

2000

Language:

english

File:

PDF, 465 KB

english, 2000

28

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

Colby, Denise A., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Chemical Reviews

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

29

Expedient Synthesis of N -Acyl Anthranilamides and β-Enamine Amides by the Rh(III)-Catalyzed Amidation of Aryl and Vinyl C–H Bonds with Isocyanates

Hesp, Kevin D., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 845 KB

english, 2011

30

ChemInform Abstract: Chiral N-Acyl-tert-butanesulfinamides: The “Safety-Catch” Principle Applied to Diastereoselective Enolate Alkylations.

Bradley J. Backes, Dean R. Dragoli, Jonathan A. Ellman

Journal:

Year:

1999

File:

PDF, 34 KB

1999

31

Applications of tert-Butanesulfinamide in the Asymmetric Synthesis of Amines

Jonathan A. Ellman

Journal:

Year:

2003

File:

PDF, 49 KB

2003

32

ChemInform Abstract: Application of Daugulis Copper-Catalyzed Direct Arylation to the Synthesis of 5-Aryl Benzotriazepines.

Sirilata Yotphan, Robert G. Bergman, Jonathan A. Ellman

Journal:

Year:

2009

File:

PDF, 21 KB

2009

33

Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models

Melissa J. Leyva, Francesco DeGiacomo, Linda S. Kaltenbach, Jennifer Holcomb, Ningzhe Zhang, Juliette Gafni, Hyunsun Park, Donald C. Lo, Guy S. Salvesen, Lisa M. Ellerby, Jonathan A. Ellman

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

34

Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D

Ellen K. Kick, Diana C. Roe, A. Geoffrey Skillman, Guangcheng Liu, Todd J.A. Ewing, Yaxiong Sun, Irwin D. Kuntz, Jonathan A. Ellman

Journal:

Chemistry & Biology

Year:

1997

Language:

english

File:

PDF, 1.16 MB

english, 1997

35

ChemInform Abstract: Highly Diastereoselective Synthesis of Tetrahydropyridines by a C—H Activation—Cyclization—Reduction Cascade.

Simon Duttwyler, Colin Lu, Arnold L. Rheingold, Robert G. Bergman, Jonathan A. Ellman

Journal:

Year:

2012

File:

PDF, 53 KB

2012

36

ChemInform Abstract: Rhodium-Catalyzed Synthesis of Branched Amines by Direct Addition of Benzamides to Imines.

Kevin D. Hesp, Robert G. Bergman, Jonathan A. Ellman

Journal:

Year:

2012

File:

PDF, 48 KB

2012

37

Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C−H Bond Activation

Lewis, Jared C., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

38

Rhodium(III)-Catalyzed Arylation of Boc-Imines via C−H Bond Functionalization

Tsai, Andy S., Tauchert, Michael E., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

39

ChemInform Abstract: Regio- and Stereoselective 1,2-Dihydropyridine Alkylation/Addition Sequence for the Synthesis of Piperidines with Quaternary Centers.

Duttwyler, Simon, Chen, Shuming, Lu, Colin, Mercado, Brandon Q., Bergman, Robert G., Ellman, Jonathan A.

Journal:

Year:

2014

Language:

english

File:

PDF, 34 KB

english, 2014

40

ChemInform Abstract: Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C-H Bond Functionalization.

Wangweerawong, Apiwat, Bergman, Robert G., Ellman, Jonathan A.

Journal:

Year:

2015

File:

PDF, 89 KB

2015

41

Synthesis of ent -Ketorfanol via a C-H Alkenylation/Torquoselective 6π Electrocyclization Cascade

Phillips, Eric M., Mesganaw, Tehetena, Patel, Ashay, Duttwyler, Simon, Mercado, Brandon Q., Houk, Kendall N., Ellman, Jonathan A.

Journal:

Angewandte Chemie

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

42

Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes)

Drag, Marcin, Mikolajczyk, Jowita, Bekes, Miklos, Reyes-Turcu, Francisca E., Ellman, Jonathan A., Wilkinson, Keith D., Salvesen, Guy S.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 630 KB

english, 2008

43

α-Branched amines by catalytic 1,1-addition of C–H bonds and aminating agents to terminal alkenes

Maity, Soham, Potter, Tyler J., Ellman, Jonathan A.

Journal:

Nature Catalysis

Year:

2019

File:

PDF, 1.30 MB

2019

44

Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C–H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines

Streit, Andrew D., Zoll, Adam J., Hoang, Gia L., Ellman, Jonathan A.

Journal:

Organic Letters

Year:

2020

Language:

english

File:

PDF, 1.24 MB

english, 2020

45

ChemInform Abstract: The tert-Butanesulfinyl Group: An Ideal Chiral Directing Group and Boc-Surrogate for the Asymmetric Synthesis and Applications of β-Amino Acids.

Tony P. Tang, Jonathan A. Ellman

Journal:

Year:

1999

File:

PDF, 35 KB

1999

46

ChemInform Abstract: Asymmetric Synthesis of Protected 1,2-Amino Alcohols Using tert-Butanesulfinyl Aldimines and Ketimines.

Tony P. Tang, Steven K. Volkman, Jonathan A. Ellman

Journal:

Year:

2002

File:

PDF, 34 KB

2002

47

Structure Activity Studies of a Novel Cytotoxic Benzodiazepine.

Anthony Boitano, Cory D. Emal, Francesco Leonetti, Neal B. Blatt, Thomas A. Dineen, Jonathan A. Ellman, William R. Roush, Anthony W. Opipari, Garc D. Glick

Journal:

Year:

2004

File:

PDF, 75 KB

2004

48

Arylation of Heterocycles via Rhodium-Catalyzed C—H Bond Functionalization.

Jared C. Lewis, Sean H. Wiedemann, Robert G. Bergman, Jonathan A. Ellman

Journal:

Year:

2004

File:

PDF, 113 KB

2004

49

Potent 4-Aminopiperidine Based Antimalarial Agents.

Kristin M. Brinner, Mary Ann Powles, Dennis M. Schmatz, Jonathan A. Ellman

Journal:

Year:

2005

File:

PDF, 11 KB

2005

50

Asymmetric α-Alkylation of N′-tert-Butanesulfinyl Amidines. Application to the Total Synthesis of (6R,7S)-7-Amino-7,8-dihydro-α-bisabolene (XIV).

Takuya Kochi, Jonathan A. Ellman

Journal:

Year:

2005

File:

PDF, 41 KB

2005

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